Parissa Zandi, Yves Panis, Dominique Debray, Olivier Bernard, Didier Houssin – 1 January 1995 – Langerhans' cell histiocytosis (LCH) represents 15% to 20% of sclerosing cholangitis (SC) in children. In LCH‐associated SC, a very poor response to chemotherapy has been reported, and spontaneous prognosis is very bad. Few cases of orthotopic liver transplantation (OLT) for LCH have been reported and little is known about the risk of recurrence and the effect of immunosuppression after OLT. Since 1986, five children (mean age ± SD, 12.6 ± 3.6 years) underwent OLT for SC complicating LCH.

Paul C. Adams, Cameron N. Ghent, David R. Grant, William J. Wall – 1 January 1995 – The objective of this study was to study the factors affecting employment after liver transplantation. The employment status and health status of 203 adult liver transplant recipients was assessed retrospectively in a survey comprising an employment questionnaire, the Sickness Impact Profile (SID), and the Medical Outcomes Survey (MOS).

Juan R. Sanabria, Aravinda Upadhya, Brendan Mullen, P. Robert C. Harvey, Steven M. Strasberg – 1 January 1995 – Because an increase in biliary deoxycholate levels seems to be a risk factor for cholesterol gallstone formation, we determined the relationship between deoxycholate levels and levels of the pronucleating protein, immunoglobulin G (Ig) in human gallbladder bile. Patients with cholesterol gallstones had a higher concentration of biliary IgG compared with a pigmented stone group and control patients.

Edward L. Krawitt – 1 January 1995

Anastasios A. Mihas – 1 January 1995

Peter W. Angus, Stephen A. Locarnini, Geoffrey W. McCaughan, Robert M. Jones, Janine S. McMillan, D. Scott Bowden – 1 January 1995 – The factors that predispose patients undergoing liver transplantation for hepatitis B virus (HBV) disease to severe recurrence of infection are unclear. In this study we examined the effect of pretransplantation infection with HBV and precore variant strains of HBV on posttransplantation outcome and allograft histology in 24 patients who survived more than 3 months after liver transplantation.

Shuhua Han, Micheal Tredger, Germana V. Gregorio, Giorgina Mieli‐Vergani, Diego Vergani – 1 January 1995 – Antibodies to liver cytosol antigen type 1 (anti‐LC1), which recognize a 60‐kd peptide contained in the liver cytosolic fraction, have been reported to define a subset of autoimmune hepatitis (AIH) either negative for other autoantibodies or positive for anti‐liver kidney microsomal antibody type 1 (LKM‐1) and to be best detected in immunodiffusion.

William M. Lee, Robert M. Galbraith, Graeme H. Watt, Robin D. Hughes, Donald D. McIntire, Brenda J. Hoffman, Roger Williams – 1 January 1995 – Plasma Gc protein sequesters actin released into the circulation after massive hepatocyte necrosis, but is greatly depleted in the process. In fulminant hepatic failure (FHF), Gc is present in serum both as a complex with actin and as unbound protein, the latter becoming completely exhausted in those patients with the most severe FHF.

Junko Kobayashi, Sadako Yamada, Hironaka Kawasaki – 1 December 1994 – To clarify the clinical significance of vitronectin, we compared the concentration of plasma vitronectin with serum fibrous markers and liver function test values in patients with chronic liver diseases. We also evaluated the vitronectin content in the liver by means of enzyme‐linked immunosorbent assay and the localization of vitronectin in liver tissue with enzyme immunohistochemistry.

Stefano Bellentani, Claudio Tiribelli, Gioconda Saccoccio, Marino Sodde, Nicoletta Fratti, Christina De Martin, Giovanni Christianini – 1 December 1994 – Data on the prevalence of chronic liver disease, derived from selected series of hospitalized patients or from mortality registers, underestimate the prevalence of chronic liver disease. The Dionysos Study is a cohort study that investigated for the first time the prevalence of chronic liver disease in a general population.