Bile acids in nonalcoholic steatohepatitis: Inserting nuclear receptors into the circle
Chiara Gabbi, Jan‐Åke Gustafsson – 26 April 2012
Issues in selecting HCV‐infected candidates for anti‐viral treatment
Anna S. Lok – 26 April 2012 – Watch the interview with the authors
Importance of patient education and monitoring among HCV‐infected patients selected for anti‐viral treatment
Corinne Wentworth‐Kotara, P.A‐C. – 26 April 2012 – Watch the interview with the authors
Treatment options for anti‐HCV treatment‐experienced patients
Peter Ferenci – 26 April 2012 – Watch the interview with the authors
The prevalence of cirrhosis and hepatocellular carcinoma in patients with human immunodeficiency virus infection
George N. Ioannou, Christopher L. Bryson, Noel S. Weiss, Richard Miller, John D. Scott, Edward J. Boyko – 24 April 2012 – Cirrhosis is a leading cause of death among patients infected with human immunodeficiency virus (HIV). We sought to determine risk factors for and time trends in the prevalence of cirrhosis, decompensated cirrhosis, and hepatocellular carcinoma (HCC) among patients diagnosed with HIV who received care in the Veterans Affairs (VA) health care system nationally between 1996 and 2009 (n = 24,040 in 2009).
Hepatitis B in the United States: A major health disparity affecting many foreign‐born populations
John W. Ward, Kathy K. Byrd – 24 April 2012
Variability of standard liver volume estimation versus software‐assisted total liver volume measurement
James J. Pomposelli, Assanee Tongyoo, Christoph Wald, Elizabeth A. Pomfret – 24 April 2012 – The estimation of the standard liver volume (SLV) is an important component of the evaluation of potential living liver donors and the surgical planning for resection for tumors. At least 16 different formulas for estimating SLV have been published in the worldwide literature. More recently, several proprietary software‐assisted image postprocessing (SAIP) programs have been developed to provide accurate volume measurements based on the actual anatomy of a specific patient.
The immunobiology of colitis and cholangitis in interleukin‐23p19 and interleukin‐17a deleted dominant negative form of transforming growth factor beta receptor type ii mice
Yugo Ando, Guo‐Xiang Yang, Masanobu Tsuda, Kazuhito Kawata, Weici Zhang, Takahiko Nakajima, Koichi Tsuneyama, Patrick Leung, Zhe‐Xiong Lian, Kazuichi Okazaki, William M. Ridgway, Gary L. Norman, Aftab A. Ansari, Xiao‐Song He, Ross L. Coppel, M. Eric Gershwin – 24 April 2012 – Dominant negative form of transforming growth factor beta receptor type II (dnTGFβRII) mice, expressing a dominant negative form of TGFβ receptor II under control of the CD4 promoter, develop autoimmune colitis and cholangitis.
Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis
Benjamin Krämer, Christian Körner, Moritz Kebschull, Andreas Glässner, Marianne Eisenhardt, Hans‐Dieter Nischalke, Michael Alexander, Tilman Sauerbruch, Ulrich Spengler, Jacob Nattermann – 24 April 2012 – Natural killer (NK) cells play a role in the early control and natural course of hepatitis C virus (HCV) infection. NK cell function is regulated by a multitude of receptors, including activating NKp46 receptor. However, reports on NKp46 in hepatitis C are controversial.
Retinoids ameliorate insulin resistance in a leptin‐dependent manner in mice
Hiroyuki Tsuchiya, Yoshito Ikeda, Yu Ebata, Chihiro Kojima, Rikutaro Katsuma, Tatsuaki Tsuruyama, Tomohiko Sakabe, Kohei Shomori, Noriko Komeda, Shoko Oshiro, Hideharu Okamoto, Kazuko Takubo, Susumu Hama, Koichi Shudo, Kentaro Kogure, Goshi Shiota – 24 April 2012 – Transgenic mice expressing dominant‐negative retinoic acid receptor (RAR) α specifically in the liver exhibit steatohepatitis, which leads to the development of liver tumors.