Lei Wang, Xiang Zhang, Lin‐Tao Jia, Si‐Jun Hu, Jing Zhao, Jian‐Dong Yang, Wei‐Hong Wen, Zhe Wang, Tao Wang, Jun Zhao, Rui‐An Wang, Yan‐Ling Meng, Yong‐Zhan Nie, Ke‐Feng Dou, Si‐Yi Chen, Li‐Bo Yao, Dai‐Ming Fan, Rui Zhang, An‐Gang Yang – 3 September 2013 – The MYC oncogene is overexpressed in hepatocellular carcinoma (HCC) and has been associated with widespread microRNA (miRNA) repression; however, the underlying mechanisms are largely unknown.

Marjon Kerkhof, Pieter Honkoop – 3 September 2013

Michael L. Volk – 31 August 2013

Ho Cheol Hong, Soon Young Hwang, Hae Yoon Choi, Hye Jin Yoo, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Dong Seop Choi, Kyung Mook Choi – 31 August 2013 – Previous studies have shown that nonalcoholic fatty liver disease (NAFLD) and sarcopenia may share pathophysiological mechanisms, such as insulin resistance, inflammation, vitamin D deficiency, and decreased physical activity. However, their direct relationship has not been investigated.

Paul C. Adams – 31 August 2013

Ling Yang, Yoon Seok Roh, Jingyi Song, Bi Zhang, Cheng Liu, Rohit Loomba, Ekihiro Seki – 30 August 2013 – Transforming growth factor beta (TGF‐β) signaling activates Smad‐ and TGF‐β‐activated kinase 1 (TAK1)‐dependent signaling to regulate cell survival, proliferation, fibrosis, and tumorigenesis. The effects of TGF‐β signaling on metabolic syndrome, including nonalcoholic fatty liver disease, remain elusive. Wild‐type (WT) and hepatocyte‐specific TGF‐β receptor type II‐deficient (Tgfbr2ΔHEP) mice were fed a choline‐deficient amino acid (CDAA)‐defined diet for 22 weeks to induce NASH.

Ling Yang, Yoon Seok Roh, Jingyi Song, Bi Zhang, Cheng Liu, Rohit Loomba, Ekihiro Seki – 30 August 2013 – Transforming growth factor beta (TGF‐β) signaling activates Smad‐ and TGF‐β‐activated kinase 1 (TAK1)‐dependent signaling to regulate cell survival, proliferation, fibrosis, and tumorigenesis. The effects of TGF‐β signaling on metabolic syndrome, including nonalcoholic fatty liver disease, remain elusive. Wild‐type (WT) and hepatocyte‐specific TGF‐β receptor type II‐deficient (Tgfbr2ΔHEP) mice were fed a choline‐deficient amino acid (CDAA)‐defined diet for 22 weeks to induce NASH.

29 August 2013

Klaas Poelstra – 28 August 2013

Wahiba Berrabah, Pierrette Aumercier, Céline Gheeraert, Hélène Dehondt, Emmanuel Bouchaert, Jérémy Alexandre, Maheul Ploton, Claire Mazuy, Sandrine Caron, Anne Tailleux, Jérôme Eeckhoute, Tony Lefebvre, Bart Staels, Philippe Lefebvre – 28 August 2013 – Bile acid metabolism is intimately linked to the control of energy homeostasis and glucose and lipid metabolism. The nuclear receptor farnesoid X receptor (FXR) plays a major role in the enterohepatic cycling of bile acids, but the impact of nutrients on bile acid homeostasis is poorly characterized.