Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

Masayuki Nagahashi, Kazuaki Takabe, Runping Liu, Kesong Peng, Xiang Wang, Yun Wang, Nitai C. Hait, Xuan Wang, Jeremy C. Allegood, Akimitsu Yamada, Tomoyoshi Aoyagi, Jie Liang, William M. Pandak, Sarah Spiegel, Phillip B. Hylemon, Huiping Zhou – 1 November 2014

CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation–induced cell death in hepatocellular carcinoma

Guo‐Dong Lu, Yang Huey Ang, Jing Zhou, Jegadeesan Tamilarasi, Benedict Yan, Yaw Chyn Lim, Supriya Srivastava, Manuel Salto‐Tellez, Kam M. Hui, Han‐Ming Shen, Long N. Nguyen, Bryan C. Tan, David L. Silver, Shing Chuan Hooi – 1 November 2014 – CCAAT enhancer binding protein α (C/EBPα) plays an essential role in cellular differentiation, growth, and energy metabolism. Here, we investigate the correlation between C/EBPα and hepatocellular carcinoma (HCC) patient outcomes and how C/EBPα protects cells against energy starvation.

Clinical outcomes of and patient satisfaction with different incision methods for donor hepatectomy in living donor liver transplantation

Suk‐Won Suh, Kwang‐Woong Lee, Jeong‐Moo Lee, YoungRok Choi, Nam‐Joon Yi, Kyung‐Suk Suh – 28 October 2014 – With the decrease in the average donor age and the increase in the proportion of female donors, both donor safety and cosmetic appearance are major concerns for some living donors in living donor liver transplantation (LDLT) because a large abdominal incision is needed that may influence the donor's quality of life. In all, 429 donors who underwent donor hepatectomy for LDLT from April 2010 to February 2013 were included in the study.

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