R. Cutler Quillin, James V. Guarrera – 26 December 2017 – A finite supply of donor organs has led many transplant centers to accept marginal liver allografts with increasing frequency. These allografts may be at higher risk of primary nonfunction, early allograft dysfunction, and other recipient complications following liver transplantation. Machine perfusion preservation is an emerging technology that limits ischemia/reperfusion injury associated with preservation and may lead to improved outcomes following transplantation.

Jasmohan S. Bajaj, Phillip B. Hylemon – 22 December 2017

Audrey Winter, Jean‐Pierre Daurès, Paul Landais – 22 December 2017

Takeo Yoshihara, Ryotaro Sakamori, Kunimaro Furuta, Minoru Shigekawa, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Takayuki Yakushijin, Tomohide Tatsumi, Yasushi Sakata, Hidetoshi Eguchi, Yoshiki Sawa, Tetsuo Takehara – 22 December 2017

Elliot B. Tapper, Fasiha Kanwal, Sumeet K. Asrani, Chanda Ho, Nadia Ovchinsky, John Poterucha, Avegail Flores, Judith E. Smith, Victor Ankoma‐Sey, Bruce Luxon, Michael L. Volk – 22 December 2017 – Patients with cirrhosis seek improvement in their symptoms, functioning, quality of life, and satisfaction with the care they receive. However, these patient‐reported outcomes (PROs) are not routinely measured for clinical care, research, or quality improvement.

Manuela Cesaretti, Nicolas Poté, Francois Cauchy, Federica Dondero, Safi Dokmak, Ailton Sepulveda, Anne Sophie Schneck, Claire Francoz, Francois Durand, Valerie Paradis, Olivier Soubrane – 22 December 2017

Heather Francis, Lindsey Kennedy, Gianfranco Alpini – 22 December 2017

Takeo Yoshihara, Ryotaro Sakamori, Kunimaro Furuta, Minoru Shigekawa, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Takayuki Yakushijin, Tomohide Tatsumi, Yasushi Sakata, Hidetoshi Eguchi, Yoshiki Sawa, Tetsuo Takehara – 22 December 2017

Yu Sun, Terytty Yang Li, Lintao Song, Cixiong Zhang, Jingyi Li, Zhi‐Zhong Lin, Sheng‐Cai Lin, Shu‐Yong Lin – 22 December 2017 – unc‐51‐like autophagy activating kinase 1 and 2 (Ulk1/2) regulate autophagy initiation under various stress conditions. However, the physiological functions of these Ser/Thr kinases are not well characterized. Here, we show that mice with liver‐specific double knockout (LDKO) of Ulk1 and Ulk2 (Ulk1/2 LDKO) are viable, but exhibit overt hepatomegaly phenotype.

Zobair M. Younossi – 22 December 2017 – Nonalcoholic fatty liver disease (NAFLD), a common cause of chronic liver disease (CLD), has a global prevalence of 25%. Its progressive form, nonalcoholic steatohepatitis (NASH), is a leading indication for liver transplantation (LT) in the United States. As a result, specialty societies, including the American Association for the Study of Liver Diseases (AASLD) and the European Association for the Study of the Liver, have developed guidance on the epidemiology, diagnosis, and treatment of NAFLD and NASH.