A hallmark symptom of cholestasis is pruritus, which can be severe and debilitating for many patients, significantly negatively impacting their quality of life. Experts present information focused on established and recently approved therapies to treat pruritus in cholestatic diseases. Speakers highlight a multistep approach to therapeutic options in pruritus, including alternative strategies in the settings of medication intolerance and difficult-to-treat pruritus. 

This comprehensive session provides an in-depth review of critical topics surrounding liver transplantation. Presenters guide attendees through the latest updates on liver transplant indications, the evaluation process, allocation systems, and different donor types including living, deceased, and expanded criteria donors. Through case studies and expert-led discussions, participants gain a robust understanding of how to navigate the complexities of liver transplant care and improve patient outcomes.

Members of the Acute-on-Chronic Liver Failure Special Interest Group present strategies to advance and optimize the care of critically ill patients with advanced liver disease and acute-on-chronic liver failure. Topics include the role of liver transplantation, optimzation of renal function, and mangement of hemodynamics and sepsis. The session concludes with a panel discussion.

Speakers present diverse registry-based studies in&nbsp;liver disease with the objectives to dissiminate evidence-based practice knowledge and enhance collaboration. Study data from the Global Alagille Alliance (GALA) study, the International Registry of Congenital Porto-Systemic Shunts (IRCPSS), and the International Multicenter Pediatric Portal Hypertension Registry (IMPPHR) are reviewed.<br />
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Experts provide an overview of reproductive health issues and pregnancy in liver transplant recipients, including the natural history of posttransplant fertility, recommended changes in immunosuppressive pharmacotherapy during pregnancy, and fetal outcomes.

This unique meet-up fosters meaningful interaction between the patient community and health care practitioners focused on those affected by MASLD/MASH.<br />
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Sponsored by: Madrigal Pharmaceuticals<br />
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Experts present information addressing the safety and efficacy of transplantation of HBsAg-positive donor organs into hepatitis B seronegative recipients and long-term management of hepatitis B post transplantation in this patient population. Topics include patient and graft survival, and posttransplant management including the role of hepatitis B immunoglobulin, long-term HBV suppressive managment, and HCC risk and surveillance.

Experts provide a primer on how to start, organize, and refine an integrated, multidisciplinary alcohol-associated liver disease (ALD) clinic. Topics addressed include creation of a business plan and troubleshooting potential pitfalls in running an integrated ALD clinic.  

Experts provide insights into the treatment of alcohol use disorder (AUD) in patients with alcohol-associated liver disease, with a focus on cirrhosis. Topics include the efficacy of FDA-approved therapeutics and off-label use of medications for AUD, and how to manage side effects of these agents. 

Topic experts discuss the risk of DILI and phenotypes of presentation from children to the elderly. Presenters review emerging and novel therapies associated with DILI, provide an update on blood-based biomarkers of DILI, and highlight research priorities to address knowledge gaps in this constantly evolving space.