Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma

Karen Man‐Fong Sze, Daniel Wai‐Hung Ho, Yung‐Tuen Chiu, Yu‐Man Tsui, Lo‐Kong Chan, Joyce Man‐Fong Lee, Kenneth Siu‐Ho Chok, Albert Chi‐Yan Chan, Chung‐Ngai Tang, Victor Wai‐Lun Tang, Irene Lai‐Oi Lo, Derek Tsz‐Wai Yau, Tan‐To Cheung, Irene Oi‐Lin Ng – 14 March 2020

Annexin A6 Is Critical to Maintain Glucose Homeostasis and Survival During Liver Regeneration in Mice

Anna Alvarez‐Guaita, Patricia Blanco‐Muñoz, Elsa Meneses‐Salas, Mohamed Wahba, Abigail H. Pollock, Jaimy Jose, Mercedes Casado, Marta Bosch, Rafael Artuch, Katharina Gaus, Albert Lu, Albert Pol, Francesc Tebar, Stephen E. Moss, Thomas Grewal, Carlos Enrich, Carles Rentero – 14 March 2020

Liver injury during highly pathogenic human coronavirus infections

Ling Xu, Jia Liu, Mengji Lu, Dongliang Yang, Xin Zheng – 14 March 2020 – The severe acute respiratory syndrome coronavirus 2 (SARS‐Cov‐2), the pathogen of 2019 novel coronavirus disease (COVID‐19), has posed a serious threat to global public health. The WHO has declared the outbreak of SARS‐CoV‐2 infection an international public health emergency. Lung lesions have been considered as the major damage caused by SARS‐CoV‐2 infection. However, liver injury has also been reported to occur during the course of the disease in severe cases.

Genetic Pathways in Nonalcoholic Fatty Liver Disease: Insights From Systems Biology

Silvia Sookoian, Carlos J. Pirola, Luca Valenti, Nicholas O. Davidson – 14 March 2020 – Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions between environmental and genetic factors. Here, we review the major pathways and dominant genetic modifiers known to be relevant players in human NAFLD and which may determine key components of the heritability of distinctive disease traits including steatosis and fibrosis.

Genetic Pathways in Nonalcoholic Fatty Liver Disease: Insights From Systems Biology

Silvia Sookoian, Carlos J. Pirola, Luca Valenti, Nicholas O. Davidson – 14 March 2020 – Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning worldwide epidemic whose etiology reflects multiple interactions between environmental and genetic factors. Here, we review the major pathways and dominant genetic modifiers known to be relevant players in human NAFLD and which may determine key components of the heritability of distinctive disease traits including steatosis and fibrosis.

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