MRP3‐Mediated Chemoresistance in Cholangiocarcinoma: Target for Chemosensitization Through Restoring SOX17 Expression
Elisa Lozano, Maitane Asensio, Laura Perez‐Silva, Jesus M. Banales, Oscar Briz, Jose J.G. Marin – 20 December 2019
Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2
Yunru Chen, Qing Li, Kangsheng Tu, Yuanguo Wang, Xianghu Wang, Dandan Liu, Chen Chen, Donglian Liu, Rendong Yang, Wei Qiu, Ningling Kang – 20 December 2019 – Transforming growth factor β (TGFβ) induces hepatic stellate cell (HSC) differentiation into tumor‐promoting myofibroblast, although underlying mechanism remains incompletely understood. Focal adhesion kinase (FAK) is activated in response to TGFβ stimulation, so it transmits TGFβ stimulus to extracellular signal‐regulated kinase and P38 mitogen‐activated protein kinase signaling.
Thrombocytopenia in Cirrhosis: A Review of Pathophysiology and Management Options
Andrew H. Moore – 20 December 2019
There Is Meaning in Thy Snores
Timucin Taner, Julie K. Heimbach – 19 December 2019
Letter to the Editor: Statins and Reduced Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B
Rui Huang, Jian Wang, Weihua Wu, Xiaomin Yan, Chao Wu – 19 December 2019
Highly Sensitive Circulating MicroRNA Panel for Accurate Detection of Hepatocellular Carcinoma in Patients With Liver Disease
Yusuke Yamamoto, Shunsuke Kondo, Juntaro Matsuzaki, Minoru Esaki, Takuji Okusaka, Kazuaki Shimada, Yoshiki Murakami, Masaru Enomoto, Akihiro Tamori, Ken Kato, Yoshiaki Aoki, Satoko Takizawa, Hiromi Sakamoto, Shumpei Niida, Fumitaka Takeshita, Takahiro Ochiya – 19 December 2019 – Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer deaths worldwide. The high mortality rate in HCC is largely due to the difficulty of early detection.
Acute‐on‐Chronic Liver Failure Prognosis Using North American Consortium for the Study of End‐Stage Liver Disease–Acute‐on‐Chronic Liver Failure Score: Paving the Road to Transplant?
Samarth S. Patel, Jasmohan S. Bajaj – 18 December 2019
Machine Learning in a Complex Disease: PREsTo Improves the Prognostication of Primary Sclerosing Cholangitis
Dennis L. Shung, David N. Assis – 18 December 2019
Mitochondrial Double‐Stranded RNA in Exosome Promotes Interleukin‐17 Production Through Toll‐Like Receptor 3 in Alcohol‐associated Liver Injury
Jun‐Hee Lee, Young‐Ri Shim, Wonhyo Seo, Myung‐Ho Kim, Won‐Mook Choi, Hee‐Hoon Kim, Ye Eun Kim, Keungmo Yang, Tom Ryu, Jong‐Min Jeong, Hei‐Gwon Choi, Hyuk Soo Eun, Seok‐Hwan Kim, Hyejin Mun, Je‐Hyun Yoon, Won‐Il Jeong – 17 December 2019
Letter to the Editor: Response to “Liver Transplantation for Acute Liver Failure Due to Dengue Fever”
Harshad Devarbhavi – 17 December 2019