Serum MicroRNA Signatures in Recovery From Acute and Chronic Liver Injury and Selection for Liver Transplantation

Siamak Salehi, Oliver D. Tavabie, Suman Verma, Mark J. W. McPhail, Farzin Farzaneh, William Bernal, Krish Menon, Kosh Agarwal, Varuna R. Aluvihare – 16 April 2020 – We previously demonstrated a distinct hepatic microRNA (miRNA) signature (down‐regulation of miRNA‐23a, ‐150, ‐ 200b, ‐503, and ‐663 and up‐regulation of miRNA‐20a) is associated with successful regeneration in auxiliary liver transplantation (ALT). This study aimed to evaluate whether the serum expression of this regeneration‐linked miRNA signature is associated with clinical outcomes in acute and chronic liver disease.

Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID‐19 Pandemic: AASLD Expert Panel Consensus Statement

Oren K. Fix, Bilal Hameed, Robert J. Fontana, Ryan M. Kwok, Brendan M. McGuire, David C. Mulligan, Daniel S. Pratt, Mark W. Russo, Michael L. Schilsky, Elizabeth C. Verna, Rohit Loomba, David E. Cohen, Jorge A. Bezerra, K. Rajender Reddy, Raymond T. Chung – 16 April 2020

The Role of Ischemia/Reperfusion Injury in Early Hepatic Allograft Dysfunction

Junbin Zhou, Jian Chen, Qiang Wei, Kourosh Saeb‐Parsy, Xiao Xu – 15 April 2020 – Liver transplantation (LT) is the only available curative treatment for patients with end‐stage liver disease. Early allograft dysfunction (EAD) is a life‐threatening complication of LT and is thought to be mediated in large part through ischemia/reperfusion injury (IRI). However, the underlying mechanisms linking IRI and EAD after LT are poorly understood.

Four Biomarkers Linked to Activation of Cluster of Differentiation 8–Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure

Mike A. Leonis, Alexander G. Miethke, Lin Fei, Sean Maynor, Catherine A. Chapin, Jacob J.H. Bleesing, Estella M. Alonso, Robert H. Squires, for the Pediatric Acute Liver Failure Study Group – 15 April 2020

Subscribe to