Evolution of Systemic Therapy for Hepatocellular Carcinoma

Richard S. Finn, Andrew X. Zhu – 7 May 2020 – Despite being one of the leading causes of cancer death globally, hepatocellular carcinoma (HCC) has historically not been the focus of novel drug development. That has changed in the past several years, with the results from a number of hallmark phase 3 studies in advanced HCC. In HCC, immune‐oncology approaches have garnered much attention; there is still a need to better understand criteria for patient selection and to optimize combination strategies to maximize the potential of these approaches.

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