Long‐term outcomes of 600 living donor liver transplants for pediatric patients at a single center

Mikiko Ueda, Fumitaka Oike, Yasuhiro Ogura, Kenji Uryuhara, Yasuhiro Fujimoto, Mureo Kasahara, Kohei Ogawa, Koichi Kozaki, Hironori Haga, Koichi Tanaka – 13 June 2006 – This report concerns the long‐term outcome of living donor liver transplantation (LDLT) for pediatric patients at a single center. Between June 1990 and December 2003, a total of 600 LDLTs, including 568 primary transplantations and 32 retransplantations, were performed for pediatric patients, who were immunosuppressed with FK506 and low‐dose corticosteroids.

Adherence to medication after liver transplantation in Scotland: A pilot study

Ronan E. O'Carroll, Lesley M. McGregor, Vivien Swanson, George Masterton, Peter C. Hayes – 13 June 2006 – This study assessed adherence to medication after liver transplantation and consisted of 2 components: a retrospective audit involving the examination of the Scottish national database, and a preliminary study assessing psychological factors implicated in poor adherence.

Predictors of clinical outcome in children undergoing orthotopic liver transplantation for acute and chronic liver disease

Chris Rhee, Kiran Narsinh, Robert S. Venick, Ricardo A. Molina, Visal Nga, Rita Engelhardt, Martín G. Martín – 1 June 2006 – The current United Network for Organ Sharing (UNOS) policy is to allocate liver grafts to pediatric patients with chronic liver disease based on the pediatric end‐stage liver disease (PELD) scoring system, while children with fulminant hepatic failure may be urgently listed as Status 1a.

Peritonitis after liver transplantation: Incidence, risk factors, microbiology profiles, and outcome

Surakit Pungpapong, Salvador Alvarez, Walter C. Hellinger, David J. Kramer, Darrin L. Willingham, Julio C. Mendez, Justin H. Nguyen, Winston R. Hewitt, Jaime Aranda‐Michel, Denise M. Harnois, Barry G. Rosser, Christopher B. Hughes, Hani P. Grewal, Raj Satyanarayana, Rolland C. Dickson, Jeffrey L. Steers, Andrew P. Keaveny – 1 June 2006 – Peritonitis occurring after liver transplantation (PLT) has been poorly characterized to date. The aims of this study were to define the incidence, risk factors, microbiology profiles, and outcome of nonlocalized PLT.

Conversion from mycophenolate mofetil to enteric‐coated mycophenolate sodium in liver transplant patients presenting gastrointestinal disorders: A pilot study

Jérôme Dumortier, Marie‐Claude Gagnieu, Janine Salandre, Olivier Guillaud, Philipe Guillem, Mustapha Adham, Olivier Boillot – 1 June 2006 – Gastrointestinal (GI) disorders are one of the main adverse events in patients treated by mycophenolic acid (MPA).

Effects of splenic artery occlusion on portal pressure in patients with cirrhosis and portal hypertension

Angelo Luca, Roberto Miraglia, Settimo Caruso, Mariapina Milazzo, Bruno Gidelli, Jaime Bosch – 1 June 2006 – The specific contribution of splenic blood inflow to portal hypertension in patients with cirrhosis is still unclear. In this study, we investigated this contribution by assessing the hemodynamic effects of transient splenic artery occlusion.

Association of hepatic iron overload with invasive fungal infection in liver transplant recipients

Jacob Alexander, Ajit P. Limaye, Cynthia W. Ko, Mary P. Bronner, Kris V. Kowdley – 1 June 2006 – Invasive fungal infection is a serious complication of orthotopic liver transplantation, but its risk factors remain incompletely defined. Iron overload has already been associated with increased risk of fungal infections, but it has not yet been assessed as a risk factor in liver transplantation. We retrospectively studied a cohort of 153 consecutive patients who underwent their first liver transplantation at a single center and who survived at least 7 days after transplantation.

Molecular adsorbent recirculating system in patients with early allograft dysfunction after liver transplantation: A pilot study

Hubert Hetz, Peter Faybik, Gabriela Berlakovich, Amir Baker, Andreas Bacher, Christopher Burghuber, Sigrid E. Sandner, Heinz Steltzer, Claus Georg Krenn – 1 June 2006 – Early allograft dysfunction (EAD) after orthotopic liver transplantation (OLT) causes marked morbidity and mortality. We conducted a prospective pilot study to assess the safety and efficacy of molecular adsorbent recirculating system (MARS) in treatment of EAD after OLT.

Outcome and quality of life in patients with polycystic liver disease after liver or combined liver‐kidney transplantation

Gabriele I. Kirchner, Kinan Rifai, Tobias Cantz, Bjoern Nashan, Christoph Terkamp, Thomas Becker, Christian Strassburg, Hannelore Barg‐Hock, Siegfried Wagner, Rainer Lück, Juergen Klempnauer, Michael P. Manns – 1 June 2006 – In advanced stages of polycystic liver disease, often associated with polycystic kidney disease, a curative therapy is liver or combined liver‐kidney transplantation. However, little is known about long‐term outcome and quality of life.

Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam

Nguyen L. Toan, Le H. Song, Peter G. Kremsner, Dinh N. Duy, Vu Q. Binh, Bernd Koeberlein, Stefan Kaiser, Reinhard Kandolf, Joseph Torresi, C.‐Thomas Bock – 25 May 2006 – Eight genotypes (A‐H) of hepatitis B virus (HBV) have been identified. However, the impact of different genotypes on the clinical course of hepatitis B infection remains controversial. We investigated the frequency and clinical outcome of HBV genotypes and genotype mixtures in HBV‐infected patients from Vietnam, Europe, and Africa.

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