Induction of long‐term liver allograft survival by delayed immunosuppression is dependent on interleukin‐10
Zhen Fan Yang, Patricia Ngai, Chi Keung Lau, David W. Ho, Ka Ho Tam, Chi Tat Lam, Ronnie T. Poon, Sheung Tat Fan – 29 March 2007 – This study aims to investigate the potential role of endogenous interleukin (IL)‐10 in long‐term liver allograft survival induced by delayed immunosuppression (FK506 days 2‐7). Liver transplantation was performed by using Dark Agouti and Lewis rats as donors and recipients, respectively. The delayed immunosuppression protocol induced indefinite allograft survival.