Comparison of two techniques of transarterial chemoembolization before liver transplantation for hepatocellular carcinoma: A case‐control study

Sébastien Dharancy, Jeanne Boitard, Thomas Decaens, Géraldine Sergent, Emmanuel Boleslawski, Christophe Duvoux, Claire Vanlemmens, Carole Meyer, Jean Gugenheim, François Durand, Olivier Boillot, Nicole Declerck, Alexandre Louvet, Valérie Canva, Olivier Romano, Olivier Ernst, Philippe Mathurin, François René Pruvot – 10 April 2007 – Supraselective transarterial chemoembolization (STACE) more efficiently targets chemotherapy delivered via the feeding arterial branches of the tumor than does conventional transarterial chemoembolization (TACE).

Early and late outcome of cardiac surgery in patients with liver cirrhosis

Farzan Filsoufi, Sacha P. Salzberg, Parwis B. Rahmanian, Thomas D. Schiano, Hussien Elsiesy, Anthony Squire, David H. Adams – 10 April 2007 – Liver cirrhosis is a major risk factor in general surgery. Few studies have reported on the outcome of cardiac surgery in these patients. Herein we report our recent experience in this high‐risk patient population according to the Child‐Turcotte‐Pugh classification and Model for End‐Stage Liver Disease (MELD) score.

Bacterial translocation during liver transplantation: A randomized trial comparing conventional with venovenous bypass vs. piggyback methods

Edson Abdala, Carlos Eduardo Sandoli Baía, Sérgio Mies, Paulo Celso Bosco Massarollo, Norma de Paula Cavalheiro, Vania Regina Mollo Baía, Conceição Aparecida Félix Inácio, Henry Corazza Sef, Antonio Alci Barone – 29 March 2007 – The aim of this study was to evaluate the bacterial translocation in liver transplantation (LT), comparing the conventional and the piggyback methods. A total of 32 patients were randomized into the 2 groups. Samples of blood were collected from the radial artery, portal vein (PV) and hepatic vein (HV), in up to 120 minutes postreperfusion.

Preservation of steatotic livers: A comparison between cold storage and machine perfusion preservation

Maud Bessems, Benedict M. Doorschodt, Joe L.P. Kolkert, Reeta L. Vetelainen, Arlene K. van Vliet, Heleen Vreeling, Jan van Marle, Thomas M. van Gulik – 29 March 2007 – Liver grafts are frequently discarded due to steatosis. Steatotic livers can be classified as suboptimal and deteriorate rapidly during hypothermic static preservation, often resulting in graft nonfunction. Hypothermic machine perfusion (MP) has been introduced for preservation of donor livers instead of cold storage (CS), resulting in superior preservation outcomes.

Liver transplantation in children with sickle‐cell disease

Kristin L. Mekeel, Max R. Langham, Regino Gonzalez‐Peralta, Shiro Fujita, Alan W. Hemming – 29 March 2007 – Severe liver disease is an unusual but potentially fatal complication of sickle‐cell disease (SCD). Liver transplantation has been complicated by ongoing SCD and thrombosis. We reviewed 214 pediatric transplants done at our institution from 1990 to 2005. Three patients were transplanted for complications of SCD, including intrahepatic cholestasis and viral hepatitis. Overall patient and graft survival was 66%. One patient died after 6 years from a subdural hematoma.

Antiinflammatory properties of IL‐10 rescue small‐for‐size liver grafts

Zhen Fan Yang, David Wing Yuen Ho, Patricia Ngai, Chi Keung Lau, Yi Zhao, Ronnie Tung Ping Poon, Sheung Tat Fan – 29 March 2007 – The present study aims to investigate the potential therapeutic role of interleukin‐10 (IL‐10) in small‐for‐size liver transplantation. A syngenic rat orthotopic liver transplantation model was performed using either whole or 40% liver volume of Lewis rats as grafts according to the experimental design. IL‐10 was given to the 40% grafts right after reperfusion, and also at 24 and 48 hours after transplantation.

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