Graft histology characteristics in long‐term survivors of pediatric liver transplantation

Udeme D. Ekong, Hector Melin‐Aldana, Roopa Seshadri, Joan Lokar, Dave Harris, Peter F. Whitington, Estella M. Alonso – 29 October 2008 – The factors that influence the long‐term histological outcome of transplanted liver allografts in children are not yet fully understood, and the role of surveillance biopsies in patients with normal graft function remains controversial. The aims of this study were to describe the long‐term graft histology of pediatric liver transplant recipients surviving at least 3 years and to analyze factors correlating with long‐term histological outcome.

Liver tumors: Pediatric population

Milton J. Finegold, Rachel A. Egler, John A. Goss, R. Paul Guillerman, Saul J. Karpen, Rajesh Krishnamurthy, Christine Ann O'Mahony – 29 October 2008 – Liver tumors in childhood are rare and are typically not detected clinically until they reach a large size and often spread within the organ or metastasize. This can make surgical resection problematic, and almost all of them require extirpation for cure.

Vasopressin decreases portal vein pressure and flow in the native liver during liver transplantation

Gebhard Wagener, Gina Gubitosa, John Renz, Milan Kinkhabwala, Tricia Brentjens, James V. Guarrera, Jean Emond, H. Thomas Lee, Donald Landry – 29 October 2008 – Vasodilation due to impaired vascular tone is common in liver failure. Vasoconstrictor drugs are almost always required during the anhepatic phase of a liver transplant to maintain blood pressure unless venovenous bypass is employed.

Paralysis in the left phrenic nerve after living‐donor liver transplantation for biliary atresia with situs inversus

Yukihiro Sanada, Koichi Mizuta, Youichi Kawano, Satoshi Egami, Makoto Hayashida, Shuji Hishikawa, Hideo Kawarasaki – 29 October 2008 – A 7‐month‐old boy with biliary atresia accompanied by situs inversus and absent inferior vena cava (IVC) underwent living‐donor liver transplantation (LDLT). Because a constriction in the recipient hepatic vein (HV) was detected during the preparation of the HV in LDLT, a dissection in the cranial direction and a total clamp of the suprahepatic IVC was performed, and the suprahepatic IVC and the graft HV were anastomosed end‐to‐end.

Liver transplantation and subsequent risk of cancer: Findings from a Canadian cohort study

Ying Jiang, Paul J. Villeneuve, Stanley S. A. Fenton, Douglas E. Schaubel, Les Lilly, Yang Mao – 29 October 2008 – Characterization of the long‐term cancer risks among liver transplant patients has been hampered by the paucity of sufficiently large cohorts. The increase over time in the number of liver transplants coupled with improved survival underscores the need to better understand associated long‐term health effects. This is a cohort study whose subjects were assembled with data from the population‐based Canadian Organ Replacement Registry.

Subscribe to