Sexual transmission of HCV among monogamous heterosexual couples: Be careful with reassuring counseling messages
Philippe Halfon – 19 February 2013
The sexual transmission rate of HCV among heterosexual couples
Bart P.X. Grady, Maria Prins, Maarten Schim Loeff – 19 February 2013
Elastin‐based molecular MRI of liver fibrosis
Josef Ehling, Matthias Bartneck, Viktor Fech, Britta Butzbach, Richard Cesati, Rene Botnar, Twan Lammers, Frank Tacke – 19 February 2013
Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation‐mediated hepatocarcinogenesis
Tamara Potikha, Evgeniy Stoyanov, Orit Pappo, Antonina Frolov, Lina Mizrahi, Deborah Olam, Temima Shnitzer‐Perlman, Ido Weiss, Neta Barashi, Amnon Peled, Gabriele Sass, Gisa Tiegs, Francoise Poirier, Gabriel A. Rabinovich, Eithan Galun, Daniel Goldenberg – 19 February 2013 – Chronic inflammation is strongly associated with an increased risk for hepatocellular carcinoma (HCC) development.
Taurolithocholate‐induced MRP2 retrieval involves MARCKS phosphorylation by protein kinase Cϵ in HUH‐NTCP Cells
Christopher M. Schonhoff, Cynthia R. L. Webster, M. Sawkat Anwer – 19 February 2013 – Taurolithocholate (TLC) acutely inhibits the biliary excretion of multidrug‐resistant associated protein 2 (Mrp2) substrates by inducing Mrp2 retrieval from the canalicular membrane, whereas cyclic adenosine monophosphate (cAMP) increases plasma membrane (PM)–MRP2. The effect of TLC may be mediated via protein kinase Cϵ (PKCϵ). Myristoylated alanine‐rich C kinase substrate (MARCKS) is a membrane‐bound F‐actin crosslinking protein and is phosphorylated by PKCs.
Reply to Elastin‐based molecular MRI of liver fibrosis
Antonella Pellicoro, John P. Iredale – 19 February 2013
Jay Donald Ostrow: The yellow giant
Claudio Tiribelli, Libor Vitek, Richard P. Wennberg – 19 February 2013
Frequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894G>A) in various racial and ethnic groups
Stuart A. Scott, Benny Liu, Irina Nazarenko, Suparna Martis, Julia Kozlitina, Yao Yang, Charina Ramirez, Yumi Kasai, Tommy Hyatt, Inga Peter, Robert J. Desnick – 19 February 2013 – Cholesteryl ester storage disease (CESD) and Wolman disease are autosomal recessive later‐onset and severe infantile disorders, respectively, which result from the deficient activity of lysosomal acid lipase (LAL). LAL is encoded by LIPA (10q23.31) and the most common mutation associated with CESD is an exon 8 splice junction mutation (c.894G>A; E8SJM), which expresses only ∼3%‐5% of normally spliced LAL.