Circulating Kidney Injury Molecule 1 Predicts Prognosis and Poor Outcome in Patients With Acetaminophen‐Induced Liver Injury

Daniel J. Antoine, Venkata S. Sabbisetti, Ben Francis, Andrea L. Jorgensen, Darren G.N. Craig, Kenneth J. Simpson, Joseph V. Bonventre, B. Kevin Park, James W. Dear – 18 April 2015 – Acute kidney injury in the context of acetaminophen (APAP; paracetamol)‐induced liver injury is an important predictor of the requirement for urgent liver transplantation (LT) to avoid death. However, the prognostic biomarker used to report kidney dysfunction (serum creatinine concentration) has suboptimal sensitivity and specificity.

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