Silvia Liu, Michael A. Nalesnik, Aatur Singhi, Michelle A. Wood‐Trageser, Parmjeet Randhawa, Bao‐Guo Ren, Abhinav Humar, Peng Liu, Yan‐Ping Yu, George C. Tseng, George Michalopoulos, Jian‐Hua Luo – 31 October 2021 – Hepatocellular carcinoma (HCC) is one of the most lethal human cancers. Liver transplantation has been an effective approach to treat liver cancer. However, significant numbers of patients with HCC experience cancer recurrence, and the selection of suitable candidates for liver transplant remains a challenge.

George Cholankeril, Alsadiq Al‐Hillan, Brandon Tarlow, Daniela Abrams, Jake S. Jacobs, Norma P. Flores, Abbas Rana, Fasiha Kanwal, John A. Goss – 31 October 2021

Jean de Ville de Goyet, Ulrich Baumann, Vincent Karam, René Adam, Silvio Nadalin, Nigel Heaton, Raymond Reding, Sophie Branchereau, Darius Mirza, Jürgen L. Klempnauer, Lutz Fischer, Piotr Kalicinski, Michele Colledan, Manuel Lopez Santamaria, Ruben H. Kleine, Christophe Chardot, Sezai Yilmaz, Murat Kilic, Olivier Boillot, Fabrizio Francesco, Wojciech G. Polak, Henkjan J. Verkade, for the European Liver, Intestine Transplant Association – 31 October 2021

Jan C. DeNofrio, Manisha Verma, Andrzej S. Kosinski, Victor Navarro, Tamar H. Taddei, Michael L. Volk, Marie Bakitas, Kavitha Ramchandran – 30 October 2021 – Palliative care (PC) benefits patients with serious illness including end‐stage liver disease (ESLD). As part of a cluster randomized trial, hepatologists were trained to deliver primary palliative care to patients with ESLD using an online course, Palliative Care Always: Hepatology (PCA:Hep). Here we present a multimethod formative evaluation (feasibility, knowledge acquisition, self‐efficacy, and practice patterns) of PCA:Hep.

Cindy Zhang, Andrew Freistaedter, Carolin Schmelas, Manuel Gunkel, Viet Loan Dao Thi, Dirk Grimm – 30 October 2021 – Hepatitis E virus (HEV) is a major public health problem with limited therapeutic options. Here, we engineered adeno‐associated viral vectors of serotype 6 (AAV6) to express short hairpin RNAs (shRNAs) against HEV transcripts with the prospect of down‐regulating HEV replication in vivo. We designed 20 different shRNAs, targeting the genome of the HEV genotype 3 (GT3) Kernow‐C1 p6 strain, for delivery upon AAV6 transduction.

Terry Cheuk‐Fung Yip, Vincent Wai‐Sun Wong, Grace Lai‐Hung Wong – 30 October 2021

30 October 2021

Vincenzo Ronca, Matteo Barabino, Roberto Santambrogio, Enrico Opocher, James Hodson, Emanuela Bertolini, Simone Birocchi, Gaetano Piccolo, PierMaria Battezzati, Marco Cattaneo, Gian Marco Podda – 29 October 2021 – In patients with cirrhosis with severe thrombocytopenia (platelet count [PC] <50 × 109/L) and undergoing invasive procedures, it is common clinical practice to increase the PC with platelet transfusions or thrombopoietin receptor agonists to reduce the risk of major periprocedural bleeding.

Christine L. Zimmer, Iva Filipovic, Martin Cornillet, Colm J. O’Rourke, Lena Berglin, Hannes Jansson, Dan Sun, Otto Strauss, Laura Hertwig, Helene Johansson, Erik Seth, Ernesto Sparrelid, Joana Dias, Hans Glaumann, Espen Melum, Ewa C. Ellis, Johan K. Sandberg, Jesper B. Andersen, Annika Bergquist, Niklas K. Björkström – 29 October 2021

Tian Lan, Shuo Jiang, Jing Zhang, Qiqing Weng, Yang Yu, Haonan Li, Song Tian, Xin Ding, Sha Hu, Yiqi Yang, Weixuan Wang, Lexun Wang, Duosheng Luo, Xue Xiao, Shenghua Piao, Qing Zhu, Xianglu Rong, Jiao Guo – 29 October 2021