Declining a Split‐Liver Offer Can Be Hazardous to Your Health
Charles A. Mouch, Sophoclis P. Alexopoulos – 18 February 2022
Implementation science: Accelerating translation of clinical evidence into practice
Michael L. Volk – 18 February 2022
Immunoglobulin M: A Neglected Serum Biomarker in Treatment‐Naive Primary Biliary Cholangitis With Normal Alkaline Phosphatase
Dawei Ding, Guoyun Xuan, Yinan Hu, Jiahao Yu, Yansheng Liu, Guanya Guo, Shuoyi Ma, Fangfang Yang, Siyuan Tian, Gang Ma, Ling Chen, Xinmin Zhou, Yulong Shang, Ying Han – 18 February 2022 – The diagnosis of primary biliary cholangitis (PBC) in patients with seropositive anti‐mitochondrial antibody (AMA) but normal alkaline phosphatase (ALP) depends on a liver biopsy. We aimed to reveal potential serum biomarkers that could suggest the necessity of a liver biopsy in such patients. Retrospective analysis was performed.
A hierarchical regulatory network ensures stable albumin transcription under various pathophysiological conditions
Rilu Feng, Kejia Kan, Carsten Sticht, Yujia Li, Shanshan Wang, Hui Liu, Chen Shao, Stefan Munker, Hanno Niess, Sai Wang, Christoph Meyer, Roman Liebe, Matthias P. Ebert, Steven Dooley, Huiguo Ding, Honglei Weng – 18 February 2022
Genome‐wide meta‐analysis identifies susceptibility loci for autoimmune hepatitis type 1
You Li, Ying Sun, Yanmin Liu, Bangmao Wang, Jia Li, Hanxiao Wang, Haiping Zhang, Xiaoyi Wang, Xu Han, Qiuxiang Lin, Yang Zhou, Lilin Hu, Yuhu Song, Jie Bao, Ling Gong, Mengying Sun, Xiaoling Yuan, Xinhe Zhang, Min Lian, Xiao Xiao, Qi Miao, Qixia Wang, Ke‐Ke Li, Shiyu Du, Anlin Ma, Yiling Li, Jie Xu, Shanhong Tang, Junping Shi, Yun Xu, Ling Yang, Jiming Zhang, Zuxiong Huang, Lu Zhou, Yong Cui, Michael F. Seldin, M. Eric Gershwin, Huiping Yan, Zhengsheng Zou, Xianbo Zuo, Ruqi Tang, Xiong Ma, the Chinese AIH Consortium – 18 February 2022
Letter to the editor: Association between proton pump inhibitor use and biliary tract cancer risk: A Swedish population‐based cohort study
Hamood Ur Rehman Chaudhry, Ahmad Hayat, Anees Ahmad – 18 February 2022
Autoimmune hepatitis in pregnancy: Pearls and pitfalls
Y. Y. Chung, Michael A. Heneghan – 18 February 2022 – Autoimmune hepatitis (AIH) in pregnancy has many unique considerations. Evidence provided from single center studies with patient level data and nationwide population studies provide valuable insight into this complex situation. Because a planned pregnancy is a safer pregnancy, preconception counseling is a crucial opportunity to optimize care and risk stratify women with AIH.
Autoimmune hepatitis in pregnancy: Pearls and pitfalls
Y. Y. Chung, Michael A. Heneghan – 18 February 2022 – Autoimmune hepatitis (AIH) in pregnancy has many unique considerations. Evidence provided from single center studies with patient level data and nationwide population studies provide valuable insight into this complex situation. Because a planned pregnancy is a safer pregnancy, preconception counseling is a crucial opportunity to optimize care and risk stratify women with AIH.
Dynamic risk profiling of HCC recurrence after curative intent liver resection
Tommy Ivanics, Carla Fiorella Murillo Perez, Marco P. A. W. Claasen, Madhukar S. Patel, Gabriela Morgenshtern, Lauren Erdman, Chaya Shwaartz, Luckshi Rajendran, Grainne M. O’Kane, Bettina E. Hansen, Sean P Cleary, Gonzalo Sapisochin – 17 February 2022
Albumin Lipidomics Reveals Meaningful Compositional Changes in Advanced Cirrhosis and Its Potential to Promote Inflammation Resolution
Mireia Casulleras, Roger Flores‐Costa, Marta Duran‐Güell, Ingrid W. Zhang, Cristina López‐Vicario, Anna Curto, Javier Fernández, Vicente Arroyo, Joan Clària – 17 February 2022 – Albumin infusions are therapeutically used to revert hypoalbuminemia and to replace the extensively oxidized albumin molecule circulating in patients with acutely decompensated (AD) cirrhosis. Because albumin has high affinity for lipids, here we characterized the albumin lipidome in patients with AD and explored the albumin effects on the release of fatty acid (FA)–derived lipid mediators by peripheral leukocytes.