Living donor liver transplantation and hepatitis C: Lessons from the learning curve?
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Jose A. Carrión, Xavier Forns – 27 December 2006
Jose A. Carrión, Xavier Forns – 27 December 2006
Faouzi Saliba, Mohamed Lakehal, Georges‐Philippe Pageaux, Bruno Roche, Claire Vanlemmens, Christophe Duvoux, Jérôme Dumortier, Ephrem Salamé, Yvon Calmus, Didier Maugendre, Diapason Study Group – 27 December 2006 – New‐onset diabetes mellitus (NODM) remains a common complication of liver transplantation (LT). We studied incidence and risk factors in 211 French patients who had undergone a primary LT between 6 and 24 months previously. This is a cross‐sectional and retrospective multicenter study. Data were collected on consecutive patients at a single routine post‐LT consultation.
See Ching Chan, Sheung Tat Fan, Chung Mau Lo, Chi Leung Liu – 27 December 2006 – By virtue of size, the right liver graft has become the workhorse of adult‐to‐adult live donor liver transplantation (ALDLT). Although favorable results of left liver ALDLT have also been reported, a head‐to‐head comparison of these 2 graft types both containing the middle hepatic vein had not been made. In this study, we compared the outcomes of 29 right liver and 16 left liver ALDLTs of comparable graft weight to recipient estimated standard liver volume ratio (GW/ESLV, 36.9% and 36.4%, respectively).
Gaia Nebbia, Frank M. Mattes, Evangelos Cholongitas, Ana Garcia‐Diaz, Dimitrios N. Samonakis, Andrew K. Burroughs, Vincent C. Emery – 27 December 2006 – Recurrence of Hepatitis C (HCV) post‐liver transplantation (LT) is universal and its course is more aggressive than in immunocompetent individuals. Human cytomegalovirus (CMV) infection is a common post‐LT infection and has immunomodulatory effects that could adversely affect the outcome of HCV. To date, the effect of HCV replication on the dynamics of CMV have not been investigated.
Scott W. Biggins, Sandy Feng – 27 December 2006
Alejandro Mejia, Neil Barshes, Glenn Halff, John Goss, W. Kenneth Washburn – 27 December 2006 – The use of split‐liver (SL) allografts continues to be an excellent option for many pediatric recipients. Patient and graft survival with this graft type are comparable to patient and graft survival with whole organ grafts. Quality‐of‐life issues, specifically growth, for SL recipients have not been compared to those of recipients of more conventional whole‐organ recipients. Pediatric recipients of SL and whole allografts at 2 institutions were identified.
Olga A. Taylor, Edwina J. Popek, James T. Albright, Neal R. Barshes, John A. Goss, Beth A. Carter – 27 December 2006
Soo Joo Choi, Mi Sook Gwak, Justin Sang Ko, Gaab Soo Kim, Hyun Joo Ahn, Mikyung Yang, Tae Soo Hahm, Sang Min Lee, Myung Hee Kim, Jae Won Joh – 27 December 2006 – The use of epidural catheters has been a subject of active debate in living liver donors because of the possible postoperative coagulation derangement and the subsequent risk of epidural hematoma. The aim of this study was to evaluate the safety of epidural catheters in relation to the changes in coagulation profile based on a review of previously published literature and the results of our 360 donors.
27 December 2006
Dieter C. Broering, Jessica Walter, Xavier Rogiers – 27 December 2006 – The major limitation in adult‐to‐adult living donor liver transplantation (LDLT) is an adequate graft size with special regard to the safety of the donor. Only 20% of the evaluated donors are suitable to donate the right liver, depending mainly on the critical remnant liver volume. We report 2 cases of adult‐to‐adult LDLT using dual grafts. In the first case we implanted a left lateral lobe together with a left lobe; in the second case we used a left lateral and a right lobe.