Simplifying hepatic venous outflow reconstruction in sequential living donor liver transplantation

See Ching Chan, Chung Mau Lo, Kelvin K. Ng, Kenneth S. Chok, Sheung Tat Fan – 28 October 2009 – The native liver of a familial amyloidotic polyneuropathy recipient who undergoes living donor liver transplantation used as a graft for sequential liver transplantation does not include the inferior vena cava. Implantation of this whole liver graft to a second recipient could be simplified by borrowing the experience from right liver living donor liver transplantation.

Adenosine restores the hepatic artery buffer response and improves survival in a porcine model of small‐for‐size syndrome

Dympna M. Kelly, Xiaocheng Zhu, Hiroaki Shiba, Samuel Irefin, Loris Trenti, Andrei Cocieru, Teresa Diago, Lian Fu Wang, Cristiano Quintini, Zhong Chen, Joan Alster, Shunichi Nakagawa, Charles Miller, Anthony Demetris, John J. Fung – 28 October 2009 – The aim of the study is to define the role of the HABR in the pathophysiology of the SFS liver graft and to demonstrate that restoration of hepatic artery flow (HAF) has a significant impact on outcome and improves survival.

Migration of allosensitizing donor myeloid dendritic cells into recipients after liver transplantation

Brenda M. Bosma, Herold J. Metselaar, Jeroen H. Gerrits, Nicole M. van Besouw, Shanta Mancham, Zwier M. A. Groothuismink, Patrick P. C. Boor, Luc J. W. van der Laan, Hugo W. Tilanus, Ernst J. Kuipers, Jaap Kwekkeboom – 28 October 2009 – It is thought, but there is no evidence, that myeloid dendritic cells (MDCs) of donor origin migrate into the recipient after clinical organ transplantation and sensitize the recipient's immune system by the direct presentation of donor allo‐antigens.

Endoscopic variceal ligation for primary prophylaxis of esophageal variceal hemorrhage in pre–liver transplant patients

Eu Jin Lim, Paul J. Gow, Peter W. Angus – 28 October 2009 – Endoscopic variceal ligation (EVL) is widely used to prevent esophageal variceal bleeding in patients with advanced cirrhosis. However, the safety and efficacy of EVL in this setting have not been clearly established. This study included 300 adult patients with cirrhosis on our liver transplant waitlist who underwent upper gastrointestinal endoscopy. Esophageal varices deemed to be at high risk of bleeding were banded until eradication or transplantation.

Survival of Clostridium perfringens sepsis in a liver transplant recipient

Geraldine C. Diaz, Thomas Boyer, John F. Renz – 28 October 2009 – Clostridium perfringens sepsis following orthotopic liver transplantation (OLT) is a rare but reported complication that historically results in mortality or emergent retransplantation (ReTx).1–7 Complications from C. perfringens emphysematous gastritis have contributed to the death of a healthy live liver donor as well.8 Herein, we describe the first documented survivor of C. perfringens sepsis following OLT managed without laparotomy or emergent ReTx. Liver Transpl 15:1469–1472, 2009. © 2009 AASLD.

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