Arun J. Sanyal, Scott L. Friedman, Arthur J. McCullough, Lara Dimick‐Santos – 29 December 2014 – Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease (CLD) in North America. It is a growing contributor to the burden of CDL requiring liver transplantation. Cirrhosis is also associated with an increased risk of hepatocellular cancer, which may occur even in the absence of cirrhosis in subjects with nonalcoholic steatohepatitis (NASH), the histological form of NAFLD associated with increased liver‐related mortality.

Arun J. Sanyal, Scott L. Friedman, Arthur J. McCullough, Lara Dimick‐Santos – 29 December 2014 – Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease (CLD) in North America. It is a growing contributor to the burden of CDL requiring liver transplantation. Cirrhosis is also associated with an increased risk of hepatocellular cancer, which may occur even in the absence of cirrhosis in subjects with nonalcoholic steatohepatitis (NASH), the histological form of NAFLD associated with increased liver‐related mortality.

Xavier Forns, Michael Charlton, Jill Denning, John G. McHutchison, William T. Symonds, Diana Brainard, Theo Brandt‐Sarif, Paul Chang, Valerie Kivett, Lluís Castells, Martín Prieto, Robert J. Fontana, Thomas F. Baumert, Audrey Coilly, Maria Carlota Londoño, François Habersetzer – 29 December 2014 – Recurrent hepatitis C virus (HCV) infection after liver transplantation (LT) is associated with accelerated progression of liver disease, frequently leading to graft loss and early death.

Jean‐François Dufour – 29 December 2014

Jia‐Bin Cai, Guo‐Ming Shi, Zhao‐Ru Dong, Ai‐Wu Ke, Hong‐Hui Ma, Qiang Gao, Zao‐Zhuo Shen, Xiao‐Yong Huang, Hao Chen, Ding‐Dang Yu, Li‐Xin Liu, Peng‐Fei Zhang, Chi Zhang, Mei‐Yu Hu, Liu‐Xiao Yang, Ying‐Hong Shi, Xiao‐Ying Wang, Zhen‐Bin Ding, Shuang‐Jian Qiu, Hui‐Chuan Sun, Jian Zhou, Yujiang G. Shi, Jia Fan – 29 December 2014 – The prognosis for hepatocellular carcinoma (HCC) remains dismal in terms of overall survival (OS), and its molecular pathogenesis has not been completely defined.

Shao‐Jung Hsu, Fa‐Yauh Lee, Sun‐Sang Wang, I‐Fang Hsin, Te‐Yueh Lin, Hui‐Chun Huang, Ching‐Chih Chang, Chiao‐Lin Chuang, Hsin‐Ling Ho, Han‐Chieh Lin, Shou‐Dong Lee – 29 December 2014 – Portal hypertension (PH), a pathophysiological derangement of liver cirrhosis, is characterized by hyperdynamic circulation, angiogenesis, and portosystemic collaterals. These may lead to lethal complications, such as variceal bleeding. Caffeine has been noted for its effects on liver inflammation, fibrogenesis, and vasoreactiveness.

Jean‐François Dufour – 29 December 2014

Umberto Baccarani, Riccardo Pravisani, Gian Luigi Adani, Dario Lorenzin, Andrea Risaliti – 26 December 2014

John B. Seal, Humberto Bohorquez, Trevor Reichman, Adam Kressel, Anand Ghanekar, Ari Cohen, Ian D. McGilvray, Mark S. Cattral, David Bruce, Paul Greig, Ian Carmody, David Grant, Markus Selzner, George Loss – 26 December 2014 – Liver transplantation (LT) with donation after circulatory death (DCD) donors has been associated with a high rate of ischemic‐type biliary strictures (ITBSs) and inferior graft survival.

Jason M. Ali, Susan E. Davies, Rebecca J. Brais, Lucy V. Randle, John R. Klinck, Michael E. D. Allison, Yining Chen, Laura Pasea, Simon F. J. Harper, Gavin J. Pettigrew – 26 December 2014 – Ischemia/reperfusion injury (IRI) that develops after liver implantation may prejudice long‐term graft survival, but it remains poorly understood. Here we correlate the severity of IRIs that were determined by histological grading of time‐zero biopsies sampled after graft revascularization with patient and graft outcomes.