Thrombolytic protocol minimizes ischemic‐type biliary complications in liver transplantation from donation after circulatory death donors
Laura C. Burlage, Shanice A. Karangwa, Ton Lisman, Paulo N. A. Martins, Robert J. Porte – 4 June 2015
Hepatocellular carcinoma surveillance in hepatitis B virus–infected individuals: Who and how?
Ka‐Kit Li, Palak J. Trivedi, Sophie Von Heimendahl, Tony Bruns, Steve T. Ward, Ye Oo, David Mutimer – 4 June 2015
Pretransplant management of basilar artery aneurysm and moyamoya disease in a child with Alagille syndrome
Marco Pavanello, Mariasavina Severino, Lorenzo D'Antiga, Lucio Castellan, Angela Calvi, Michele Colledan, Carlo Gandolfo – 4 June 2015
Pure laparoscopic management of early biliary leakage after liver transplantation: Abdominal lavage and T‐Tube placement
Ailton Sepulveda, Raffaele Brustia, Fabiano Perdigao, Olivier Soubrane, Olivier Scatton – 4 June 2015
Safety and Efficacy of Simeprevir/Sofosbuvir in Hepatitis C–Infected Patients With Compensated and Decompensated Cirrhosis
Varun Saxena, Lisa Nyberg, Marypat Pauly, Aditi Dasgupta, Anders Nyberg, Barbara Piasecki, Bradley Winston, Jacquelyn Redd, Joanna Ready, Norah A. Terrault – 1 June 2015 – Risks and benefits of simeprevir plus sofosbuvir (SIM+SOF) in patients with advanced cirrhosis are unknown. We assessed the safety and sustained virological responses (SVR) of SIM+SOF with and without ribavirin (RBV) in patients with Child‐Pugh (CP)‐B/C versus CP‐A cirrhosis and compared to matched untreated controls.
A clinician's guide to drug‐drug interactions with direct‐acting antiviral agents for the treatment of hepatitis C viral infection
Travis B. Dick, Lance S. Lindberg, Debra D. Ramirez, Michael R. Charlton – 29 May 2015 – The US Food and Drug Administration has recently approved a number of new direct‐acting antiviral agents for the treatment of chronic hepatitis C virus that have significantly increased the likelihood of a virological cure. These agents are highly effective but present a substantial risk for a host of clinically relevant drug‐drug interactions. These interactions must be considered both when starting and stopping any medication, including over‐the‐counter medications and herbal supplements.
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Kheng Choon Lim, Pierce K.H. Chow – 29 May 2015
A clinician's guide to drug‐drug interactions with direct‐acting antiviral agents for the treatment of hepatitis C viral infection
Travis B. Dick, Lance S. Lindberg, Debra D. Ramirez, Michael R. Charlton – 29 May 2015 – The US Food and Drug Administration has recently approved a number of new direct‐acting antiviral agents for the treatment of chronic hepatitis C virus that have significantly increased the likelihood of a virological cure. These agents are highly effective but present a substantial risk for a host of clinically relevant drug‐drug interactions. These interactions must be considered both when starting and stopping any medication, including over‐the‐counter medications and herbal supplements.
Short‐ or long‐term high‐fat diet feeding plus acute ethanol binge synergistically induce acute liver injury in mice: An important role for CXCL1
Binxia Chang, Ming‐Jiang Xu, Zhou Zhou, Yan Cai, Man Li, Wei Wang, Dechun Feng, Adeline Bertola, Hua Wang, George Kunos, Bin Gao – 29 May 2015 – Obesity and alcohol consumption often coexist and work synergistically to promote steatohepatitis; however, the underlying mechanisms remain obscure. Here, we demonstrate that feeding mice a high‐fat diet (HFD) for as little as 3 days markedly exacerbated acute ethanol binge–induced liver neutrophil infiltration and injury. Feeding mice with an HFD for 3 months plus a single binge of ethanol induced much more severe steatohepatitis.