Hepatotoxicity
Hepatotoxicity is a phenotype of liver cell injury due to a multitude of causes including drugs, toxins, herbal and dietary supplements, and other agents. The goal of the AASLD Hepatotoxicity SIG is to promote and encourage research, education, and awareness regarding human hepatotoxicity. As such, individuals with any of the following interests and expertise are encouraged to partake in SIG activities.
- Drug hepatotoxicity
- Animal and cell culture models of hepatotoxicity
- Intrinsic and extrinsic mechanisms of hepatocyte death
- Pharmacogenomics
- Pharmacoepidemiology
- Herbal and dietary supplement induced liver injury
- Regulatory issues involving drugs and HDS products
- Acute Liver failure
- Liver transplantation
- Treatments for acute and chronic hepatotoxicity
- Liver histopathology
- Adverse drug events
- Drug pharmacokinetics and pharmacodynamics
- Nomenclature of hepatotoxicity
SIG Leadership
- Chair
- Lily Dara, MD
- Vice Chair
- James P. Luyendyk, PhD
- Communication Lead
- Max Garcia, BA/BS
- Education Leads
- Udayan Apte, PhD, DABT, FAASLD
- Dina Halegoua-De Marzio, MD, FAASLD
- Trainee Lead
- Layla Shojaie, M.D.
- SIG Steering Committee Members
- Burcin Ekser, MD, PhD
- Mitchell McGill, PhD, NRCC
- Melissa Palmer, MD, MD, FAASLD
- Staff Liaisons
- Akuender Dot, MPH
- Julie Hoffman, MBA
- Member
- Bharat Bhushan, PhD