Experts in the field of inpatient hepatology care and quality improvement outline the challenges and practical patient-oriented and health system-oriented solutions to improve access to care; optimize inpatient clinical care; and provide patient-centered, compassionate care for persons hospitalized with decompensated cirrhosis. Covered topics include the management of ascites, acute-on-chronic liver failure, alcohol-associated hepatitis, and other complications of decompensated cirrhosis. Each presentation includes a discussion of health care disparities and strategies to mitigate these disparities.