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American Association for the Study of Liver Diseases and Latin American Association for the Study of the Liver Joint Symposium: Challenges in Drug-Induced Liver Injury, a Tale of Two Continents

Description

The America Association for the Study of Liver Diseases and the Latin American Association for the Study of the Liver joint symposium focuses on the experiences of investigators in Latin America and the United States with hepatotoxicity due to drugs and herbal and dietary supplements (HDSs). The first part of the session focuses on the epidemiology, prevalence, and increasing incidence of hepatotoxicity due to HDSs. Given increasing HDS use and availability (including online), presenters stress the importance of learning about new compounds, trends in HDS use, and potential new toxins for all hepatologists and other health care professionals practicing in the field to be aware of. The second portion of the symposium focuses on drug-induced autoimmune-like hepatitis (DI-ALH), a clinical challenge in many cases of hepatotoxicity. In this segment, experts discuss the presentation, diagnosis, and management of DI-ALH, and how to differentiate it from de novo autoimmune hepatitis.

 

Presentations

11:00 AM - 11:05 AM
Nov 17 2024
San Diego, CA

Welcome

Lily Dara, MD, Moderator
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
11:05 AM - 11:20 AM
Nov 17 2024
San Diego, CA

Herbal and Dietary Supplement Induced Hepatotoxicity: What's Hot in Latin America?

Fernando Bessone Professor, MD, PhD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
11:20 AM - 11:35 AM
Nov 17 2024
San Diego, CA

Not All Things in Nature Are Safe: The Rising Incidence of Herbal and Dietary Supplement Hepatotoxicity in the United States and Around the World

Dina Halegoua-DeMarzio, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
11:35 AM - 11:50 AM
Nov 17 2024
San Diego, CA

Drug-Induced Autoimmune-Like Hepatitis: Common Agents, Human Leukocyte Antigen Risk Factors, and Lessons Learned From the Drug-Induced Liver Injury Due to Nitrofurantoin Cohort

Naga P Chalasani, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
11:50 AM - 12:05 PM
Nov 17 2024
San Diego, CA

Drug-Induced Autoimmune-Like Hepatitis in the Latin Drug-Induced Liver Injury Cohort: Diagnostic Challenges and Outcomes

Nelia Hernandez, MD, Presenter
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
12:05 PM - 12:25 PM
Nov 17 2024
San Diego, CA

Q&A/Panel Discussion

Nelia Hernandez, MD, Moderator
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury
12:25 PM - 12:30 PM
Nov 17 2024
San Diego, CA

Closing

Lily Dara, MD, Chair
Acute Liver Failure
Acute-on-Chronic Liver Failure
Drug-Induced Liver Injury

Objectives

  • Identify the most common herbal and dietary supplements (HDSs) responsible for cases of hepatotoxicity in North America and South America.
  • Review emerging data on HLA associations with DILI due to HDSs.
  • Outline the diagnosis and management of drug-induced autoimmune-like hepatitis.