Dr. David E. Kaplan is an Professor of Medicine and Director of Hepatology at the Perelman School of Medicine at the University of Pennsylvania. Dr. Kaplan has served as Director of Hepatology at the Corporal Michael J. Crescenz Veterans Administration Medical Center where he has organized a regional hepatocellular carcinoma tumor board since 2014 with innovations recognized by the VA Diffusion of Excellence program. He has held multiple committee leadership roles in the AASLD including being the current Chairperson of the Liver Cancer SIG. He is an active clinician and mentor. Previous research focused on antigen-specific T-cell dysfunction in liver cancer and B-cell dysfunction related to cirrhosis, a key component of cirrhosis associated-immunodeficiency. His research currently focuses on outcomes and clinical research in cirrhosis, portal hypertension, and hepatocellular carcinoma.