MTE #33: Matrix Stiffness, Liver Injury, and Cancer (Ticketed)

Nov 18 2024
Convention Center: Room 30 E
7:00 AM - 7:45 AM
Ticketed Event

World Class Speakers

Natalie Torok, MD, MSc, AGAF, FAASLD
Discussion Leader

Natalie Torok, MD, MSc, AGAF, FAASLD

Stanford University
Rebecca G Wells, MD
Discussion Leader

Rebecca G Wells, MD

University of Pennsylvania

Description

Experts discuss the relationships between matrix stiffness, liver injury, and carcinogenesis. Presenters highlight the effects of steatosis on hepatic stellate cell activation and subsequent promotion of fibrogenesis; how liver stiffness due to chronic injury perpetuates liver disease processes; and how steatosis and steatohepatitis promote carcinogenesis through regulation of matrix stiffness. 

Journey Maps

Objectives

  • Review the mechanism by which liver stiffness due to chronic injury perpetuates the liver disease process.
  • Discuss how steatosis impacts hepatic stellate cell activation and the promotion of fibrogenesis.
  • Describe how steatohepatitis and steatosis promote carcinogenesis.