Experts discuss how to diagnose, treat, and prevent coinfections with HAV, HBV, HDV, HEV, and HIV in persons with acute or chronic HCV infection. Topics include clinical and laboratory assessment of HCV-infected persons with other types of viral hepatitis; treatment and follow-up strategies regarding coinfections with HAV, HBV, HDV, and/or HEV among HCV-infected persons; and prevention and consequences of coinfections among HCV-infected persons.