Matrix Stiffness, Liver Injury, and Cancer

Description

Experts discuss the relationships between matrix stiffness, liver injury, and carcinogenesis. Presenters highlight the effects of steatosis on hepatic stellate cell activation and subsequent promotion of fibrogenesis; how liver stiffness due to chronic injury perpetuates liver disease processes; and how steatosis and steatohepatitis promote carcinogenesis through regulation of matrix stiffness.