Inflammation and Immune Dysregulation in Pediatric Acute Liver Failure

Description

Pediatric acute liver failure (ALF) is a dynamic, life threatening condition of disparate etiology. In a subset of patients, most commonly those with an indeterminant etiology, patients appear to have evidence of immune-mediated liver injury driven by untethered inflammatory responses. In this session, experts discuss the current understanding of the inflammatory and immune mechanisms driving pediatric ALF and efforts to better identify potential therapies to improve morbidity and mortality.