Don't Be Scarred: Basic Fibrosis Research
Nov
13
2023
Room 304/306
-
Hynes Convention Center
2:00
- 3:30 PM EST
Speakers
Description
Basic science talks that examine mechanisms of hepatic fibrosis and stellate cell biology
Abstracts
- HEPATIC STELLATE CELL-SPECIFIC GLYCOLYSIS REGULATES SPATIAL GENE ZONATION AND CELLULAR INTERACTIONS TO PROMOTE IN VIVO LIVER FIBROSIS.
- EXTRACELLULAR MATRIX PROTEIN 1 ATTENUATES HEPATIC FIBROSIS BY INHIBITING PROTEASE-MEDIATED LATENT TGF-β1 ACTIVATION
- MACROPHAGE HETEROGENEITY DURING MASH REGRESSION UNVEILS MULTIFACETED TREM2 DEPENDENT MECHANISMS THAT FACILITATE MASH AND FIBROSIS RESOLUTION
- IDENTIFICATION OF ANTI-FIBROTIC microRNAs ENRICHED IN EXTRACELLULAR VESICLES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS IN PATIENTS WITH DECOMPENSATED LIVER CIRRHOSIS.
- ER-ASSOCIATED PROTEIN DEGRADATION AS A POTENTIAL ANTI-FIBROTIC TARGET IN HEPATIC STELLATE CELLS
Objectives
- Learn about newly identified mechanisms leading to hepatic fibrosis or resolution of hepatic fibrosis
- Learn about pathways that lead to hepatic fibrosis and that might be amenable to therapy
- Learn about a stellate cell-dependent pathway that may promote hepatocellular cancer