Decoding the Immunological Tango: Unraveling the Complex Interplay Between Inflammation and Liver Disease
Nov
13
2023
Ballroom A
-
Hynes Convention Center
4:30
- 6:00 PM EST
Description
A broad examination of inflammatory mediators, mechanisms of inflammation and potential targeted strategies in liver disease driven by inflammation and inflammatory cells.
Abstracts
- HEPATOCYTE DELETION OF REGULATORY T CELLS BY ENCLYSIS IS INCREASED IN AUTOIMMUNE HEPATITIS COMPARED TO MASH AND CAN BE TOGGLED BY PPARΑ AGONISTS AND ANTAGONISTS
- CHOLANGIOCYTE-MEDIATED INFILTRATION OF NEUTROPHILS IN THE PERI-PORTAL REGION INDUCES OXIDATIVE STRESS IN PRIMARY SCLEROSING CHOLANGITIS
- IMMUNOLOGICAL PROFILE ASSOCIATED WITH SEX DISPARITY OF CHOLESTATIC LIVER INJURY IN Mdr2-/- MICE
- TARGETING OF INFLAMMATORY MONOCYTES VIA CCL2/CCR2 SIGNALING AS A THERAPEUTIC STRATEGY AGAINST AUTOIMMUNE HEPATITIS BY USING MACROPHAGE-DERIVED EXTRACELLULAR VESICLES
- B CELL ACTIVATION IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS: METABOLIC SHIFTS AND IMPLICATIONS FOR ANTIGEN-SPECIFIC RESPONSES
Objectives
- Elucidate cellular crosstalk drivers in cholestatic, NASH, AIH and liver cancer.
- To understand the role of immune cells and adaptive immunity in animal models and human patients.
- To uncover potential targets directed at inflammation or specific immune cells in the course of inflammatory-driven liver disease.