Basic Science Plenary

Description

Presidential Basic Science Plenary

Abstracts

• MODELLING PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 1 USING PATIENT-SPECIFIC INDUCED PLURIPOTENT STEM CELLS
• MiR150 DEFICIENCY IN MACROPHAGES IMPROVES ALCOHOL INDUCED HEPATIC STEATOSIS VIA TRANSFERRING THYROID HORMONE RECEPTOR Β ENRICHED EVS TARGETING ADIPOSE TISSUE-LIVER AXIS: THYROID HORMONE RECEPTOR Β, A PROMISING THERAPEUTIC TARGET IN ALD
• INHIBITION OF GUT BACTERIAL BILE SALT HYDROLASES (BSHS) ATTENUATES EARLY NON-ALCOHOLIC STEATOHEPATITIS (NASH) AND NASH WITH FIBROSIS
• HEPATITIS B VIRUS INFECTION OF PRIMARY AND PLURIPOTENT STEM CELL DERIVED MULTICELLULAR HEPATIC SPHEROIDS REVEALS COMPLEX INTRACELLULAR AND INTERCELLULAR INTERACTIONS AND HOST RESPONSES.
• LIVER SINUSOIDAL ENDOTHELIAL CELLS GLYCOGEN SYNTHASE KINASE 3 ACTIVATION PROMOTES LIVER INFLAMMATION AND PORTAL HYPERTENSION IN MURINE MASH