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Friday, September 15, 2017 - 8:00 am to Saturday, September 16, 2017 - 12:00 pm
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2017 Single Topic Conference

Acute on Chronic Liver Failure: Is it Ready for Clinical Practice?
Chicago, IL, September 15 – 16, 2017 

Program Chairs

  • Florence Wong, MD
  • Jasmohan S. Bajaj, MD, FAASLD

Location

  • The Westin Chicago River North
    Chicago, IL 

Learning Objectives:

  • To discuss the diagnosis and natural history of ACLF
  • To understand the pathophysiology of ACLF
  • To learn about the therapies for the various organ failures that are part of the syndrome of ACLF
  • To develop strategies for the prevention of ACLF

Conference Description/Need Statement

To provide updated information on Acute on Chronic Liver Failure (ACLF) syndrome including its pathogenesis and evolving therapies.

Continuing Education

CME: 10.5 AMA PRA Category 1 CreditsTM

In the schedule below, it should be noted that breakfast will be served at 7 am on both days.

Session I: Pathophysiology of ACLF

Friday, September 15, 2017 
Moderators: Jasmohan S. Bajaj, MD, FAASLD and Patrick S. Kamath, MD

  • 8:00 am – 8:20 am    
    Introducing the Syndrome of ACLF
    Florence Wong, MD 
  • 8:20 am – 8:45 am  
    Inflammation in the Pathogenesis of ACLF: Infective Versus Non-infective
    Gyongyi Szabo, MD, PhD, FAASLD 
  • 8:45 am – 9:10 am    
    Mechanisms Linking Inflammation to ACLF: Is it via Immune Modulation or via Systemic Circulatory Dysfunction? 
    Richard Moreau, MD 
  • 9:10 am – 9:40 am    
    Q&A 
  • 9:40 am – 10:10 am  
    Break
     

Session II: Clinical Experience in Organ Failures Throughout the World

Friday, September 15, 2017
Moderators: K. Rajender Reddy, MD, FAASLD and Jody C. Olson, MD 

  • 10:10 am – 10:25 am    
    Asian Experience
    Shiv K. Sarin, MD, FAASLD 
  • 10:25 am – 10:40 am     
    European Experience
    Vicente Arroyo, MD, PhD 
  • 10:40 am – 10:55 am  
    North American Experience 
    Jasmohan S. Bajaj, MD, FAASLD 
  • 10:55 am – 11:15 am    
    Towards a Unified Definition of ACLF
    Patrick S. Kamath, MD 
  • 11:15 am – 11:45 am      
    Q&A
  • Noon – 1:00 pm    
    Lunch

Session III: Predisposing and Precipitating Factors

Friday, September 15, 2017
Moderators: Gyongyi Szabo, MD, PhD, FAASLD and Puneeta Tandon, MD, FRCPC

  • 1:00 pm – 1:20 pm    
    Co-morbid Conditions and Aging
    Jennifer C. Lai, MD 
  • 1:20 pm – 1:50 pm    
    Sepsis/Infection
    Richard Moreau, MD 
  • 1:50 pm – 2:10 pm    
    Surgery
    Patrick S. Kamath, MD 
  • 2:10 pm – 2:30 pm    
    Alcohol as a Precipitant of ACLF
    Gyongyi Szabo, MD, PhD, FAASLD
  • 2:30 pm – 2:50 pm    
    Q&A 
  • 2:50 pm – 3:10 pm    
    Break

Session IV: Individual Extra-Hepatic Organ Failures

Friday, September 15, 2017
Moderators: Constantine J. Karvellas, MD, SM, FRCPC and Shiv K. Sarin, MD, FAASLD

  • 3:10 pm – 3:40 pm     
    Lungs and Cardiovascular 
    Jody C. Olson, MD 
  • 3:40 pm – 4:05 pm    
    Kidney
    Florence Wong, MD
  • 4:05 pm – 4:30 pm    
    Brain
    Jasmohan S. Bajaj, MD, FAASLD 
  • 4:30 pm – 5:00 pm     
    Q&A
  • 5:30 pm – 7:00 pm    
    Poster Reception

Session V: Treatment and Prevention of ACLF

Saturday, September 16, 2017  
Moderators: Jennifer C. Lai, MD and Richard Moreau, MD

  • 8:00 am – 8:20 am    
    Non-infective Precipitating Factor Treatment Including MARS and Dialysis
    Hugo E. Vargas, MD, FAASLD 
  • 8:20 am – 8:40 am    
    Changing Landscape of Sepsis Therapy Including Albumin
    Puneeta Tandon, MD, FRCPC
  • 8:40 am – 9:00 am    
    Prevention of ACLF: Is Pre-emptive Treatment the Appropriate Choice? 
    Constantine J. Karvellas, MD, SM, FRCPC 
  • 9:00 am – 9:30 am    
    Q&A 
  • 9:30 am – 10:00 am    
    Break

Session VI: Transplant vs. Palliation

Saturday, September 16, 2017
Moderators: Florence Wong, MD and Hugo E. Vargas, MD, FAASLD

  • 10:00 am – 10:20 am     
    Transplant and ACLF: North American Experience
    K. Rajender Reddy, MD, FAASLD
  • 10:20 am – 10:40 am     
    Transplant and ACLF: European Experience
    Thierry Gustot, MD, PhD 
  • 10:40 am – 11:00 am     
    When is Transplant a Futile Option and Enough is Enough
    Jennifer C. Lai, MD 
  • 11:00 am – 11:20 am    
    Palliative Care After Discharge
    Puneeta Tandon, MD, FRCPC
  • 11:20 am – 11:50 pm    
    Q&A
  • 11:50 am – 12:00 pm    
    Conference Summary and Wrap-Up
    Jasmohan S. Bajaj, MD, FAASLD 
  • 12:00 pm     
    Adjourn